The RK lab is an interdisciplinary research group focused on understanding prokaryotic and eukaryotic chemotaxis and the interplay between cellular behaviour and disease diagnosis. We are interested in a broad range of topics in quantitative microbiology, cellular biophysics and lab-on-a-chip devices. We use bacteria and eukaryotic cells like Dictyostelium discoideum (cellular slime mold), macrophages, HL60, Hela cells. Our primary focus is quantitative analysis of the organisation, especially cytoskeletal and molecular motors protein distribution during migration. Using a combination of imaging, analysis, and modelling, my group identifies information contained in the structures and dynamics of living systems – from intracellular assemblies to cell groups. Our research seeks to 1) develop a microfluidic-based device for disease diagnosis, particularly infection, and 2) cell-cell and cell-substrate adhesion during chemotaxis. We also look into the 3) understanding of the dynamics of biofilm formation exploiting cellular motility.
Bacteria
Funded By
©